If your teeth have ever felt fuzzy after skipping a brushing, you’ve encountered biofilm—a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on devices like catheters and implants.
The Dehesh Lab recently published a study in Nature Communications identifying MEcPP, a conserved metabolite found in Gram-negative and some Gram-positive bacteria, as well as plastid-bearing organisms, as a key inhibitor of Escherichia coli biofilm formation. Biofilms, microbial communities encased in an extracellular matrix, drive antibiotic resistance, persistent infections, and equipment fouling, posing significant medical...
The National Academy of Sciences is governed by a 17-member Council, which includes five officers and 12 councilors elected from among the Academy membership. Its staff is headed by the NAS Executive Officer.
With age-related conditions like cardiovascular disease, diabetes, and dementia on the rise, the University of California, Riverside, is joining a major effort to develop treatments that delay aging and improve life for older adults.
Dr. Hailing Jin and Dr. Julia Bailey-Serres have again been recognized as highly cited researchers in the “Clarivate Analytics’ Highly Cited Researchers list,” highlighting their groundbreaking scientific contributions!
In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A University of California, Riverside team of scientists has used a novel approach to identify protein degraders that target Pin1, a protein involved in pancreatic cancer development.
Professor Katayoon “Katie” Dehesh knows all about planting and replanting roots — in biology and in life. When Dehesh escaped from Iran more than 40 years ago, she had one single goal in mind: education. She loved learning and was always curious about the biological life that surrounded her world in Iran. But in 1980...
Simon "Niels" Groen and coauthor Sophie Zaaijer published an article in Human Genomics regarding melanin reducing the effect of certain drugs. The work advocates that researchers include more diversity in genetic backgrounds for pharmaceutical development, especially when creating computer models or conducting clinical trials.
CIDVR Director Karine Le Roch, in collaboration with other researchers with UC Irvine and Yale School of Medicine, published a report in Science about the efficacy of the new MED6-189 drug against malaria parasites in humans.
Daniel Petras and Mingxun Wang published a new process for computational analytics of metabolites and pollutants in Nature Protocols. The work is part of the Virtual Multiomics Lab (VMOL) a collaborative community of researchers in chemical analysis.
The article was edited by our own Natasha Raikhel, an Associate Editor or PNAS. This article is unusual for a broad science journal because it highlights art and science in the announcement of this year’s Lasker Awards for scientific achievements. Natasha, now an emeritus Distinguished Professor, was the visionary originator of CEPCEB and a former...
Ding lab aims to prevent virus transmission in plants by pinpointing the immune pathway that preventing transmission from parent to progeny, also called vertical transmission.
Robert Jinkerson spoke to ABC news about his work with fellow UCR researcher Martha Orozco-Cardenas to grow tomatoes with acetate instead of light, for applications in future space exploration. Jinkerson also recently lead team Nolux to a $250,000 runner-up prize in NASA's Deep Space Food Challenge with their system to grow mushrooms in the dark.
